超声联合麻醉深度监测应用全身麻醉Meta分析

Objective To systematically evaluate the effect of ultrasound-guided nerve block combined with anesthesia depth monitoring on general anesthesia. Methods We searched PubMed, Web of Science, and the Chinese databases including CNKI, Wanfang, and VIP to comprehensively collect relevant randomized controlled trials(RCT) articles published from January 2020 to March 2026. Literature screening, data extraction, and bias risk assessment were independently performed by two researchers independently in duplicate and cross-checked. Finally, meta-analysis was conducted using RevMan 5.3 software. Results A total of 9 studies involving 834 patients were included. The combined group used less perioperative analgesic and sedative drugs than the control group(P<0.001). Subgroup analysis based on the control setting showed significant benefit in the “combined ultrasound-guided block or not” subgroup(P<0.001), while the “block or monitoring protocol optimization” subgroup showed no statistically significant difference(P=0.146). The extubation time after surgery was shorter in the combined group than in the control group(P=0.002), and early postoperative resting visual analogue scale(VAS) scores were lower than those in the control group(P<0.001). There was no statistically significant difference in the incidence of anesthesia-related adverse reactions between the two groups(P=0.053). Conclusion Under the guidance of anesthesia depth monitoring, combining ultrasound-guided nerve block can reduce perioperative analgesic and sedative drug use, shorten extubation time, and relieve early postoperative pain in patients undergoing general anesthesia. However, the heterogeneity of the included studies is relatively high, and the conclusion needs to be verified by more high-quality RCT.