ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-05-068 检验与方法 2025, 1(05): 149-152

全血C反应蛋白联合血常规检验在细菌感染性疾病诊断中的价值分析

务川仡佬族苗族自治县中医医院

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摘要

目的 研究临床诊断细菌感染性疾病使用全血C反应蛋白、血常规联合的价值。方法 研究以2022年10月到2024年10月126例疑似患细菌感染性疾病患者为研究对象,诊断方式分别包括全血C反应蛋白、血常规检验、细菌培养,以细菌培养结果为“金标准”。对单独检验、联合检验的价值展开分析。结果 “金标准”诊断78例细菌感染性疾病,48例非细菌感染性疾病。诊断效能方面,均为联合检验诊断结果高于单一全血C反应蛋白、单一血常规检验(P<0.05),联合检验Kappa>0.8。细菌感染组的全血C反应蛋白与血常规比非细菌感染组高(P<0.05)。结论 联合使用血常规和全血C反应蛋白检验的诊断效能显著,在提高细菌感染性疾病的早期诊断率方面更具优势。

Abstract

Objective Discussion on the value of combining whole blood C-reactive protein with blood routine in the clinical diagnosis of bacterial infectious diseases. Methods The study included 126 patients suspected of bacterial infectious diseases from October 2022 to October 2024. All patients received whole blood C-reactive protein, blood routine test and bacterial culture. The results of bacterial culture were taken as the “gold standard”. This study evaluated the diagnostic efficacy indicators of single whole blood C-reactive protein test, single blood routine test, and combined test. According to the “gold standard”, patients were divided into the bacterial infection group and the non-bacterial infection group, and the single method for whole blood C-reactive protein detection and blood routine test and combined test of whole blood C-reactive protein with blood routine was compared. Results 78 cases of bacterial infectious diseases and 48 cases of non-bacterial infectious diseases were diagnosed by the “gold standard”. The sensitivity, specificity and accuracy of combined tests in the diagnosis of bacterial infectious diseases were higher than those of single whole blood C-reactive protein and single blood routine tests(P<0.05), joint inspection showed Kappa>0.8. Bacterial whole blood C-reactive protein and infection group were higher than those in the non-bacterial infection group(P<0.05). Conclusion The joint inspection of whole blood C-reactive protein and blood routine examination has a high diagnostic efficiency in the diagnosis of bacterial infectious diseases, which is helpful to improve the early diagnosis rate of bacterial infectious diseases.

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[1]吴志远.全血C反应蛋白联合血常规检验在细菌感染性疾病诊断中的价值分析[J].疾病预防与控制,2025,1(05):149-152.